Hand Pair and Ef-Hand - Free people check

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Structural and Mechanistic Insights into STIM1-Mediated Cell Press

www.cell.com

gether, the EF-hand pair mediates mutually indis- pensable hydrophobic interactions between the. EF-hand and SAM domains. Structurally critical mu- tations in the canonical EF-hand, ''hidden'' EF- hand, or SAM domain disrupt Ca2+ sensitivity in olig- omerization via destabilization of the entire EF-SAM.

Store-operated Ca2+ entry (SOCE) pathways: Emerging signaling...

books.google.de

The 3D structure also exposes a short a-helix, not apparent in the primary sequence, which links the EF-hand pair to the five-helix bundle SAM domain. Overall ...

Ca(2+) dissociation from the C-terminal EF-hand pair in calmodulin: a ...

www.ncbi.nlm.nih.gov

FEBS Lett Apr 16;582(9): doi: j.febslet Epub Mar 17. Ca(2+) dissociation from the C-terminal EF-hand pair in calmodulin: a steered molecular dynamics study. Zhang Y(1), Tan H, Lu Y, Jia Z, Chen G. Author information: (1)Department of Chemistry, Beijing Normal University, ...

Crystal structure of a pair of follistatin-like and EF-hand...

www.ncbi.nlm.nih.gov

The two distinct domains interact through a small interface that involves the EF- hand pair of the EC domain. Residues implicated in cell binding, inhibition of cell ...

Target selectivity in EF-hand calcium binding proteins | Request PDF

www.researchgate.net

Each EF-hand pair coordinates a single Ca 2þ ion resulting in increased interhelical angles [43], yet the clefts do not show any evidence for intramolecular or homotypic intermolecular protein interactions in the available structures, contrary to other EF-hand proteins [44][45][46][47][48]. Furthermore ...

Structure of a novel extracellular Ca2+-binding module in BM

www.nature.com

... motif found in many cytosolic Ca2+-modulated proteins. Here we report the crystal structure at 2.0 Å resolution of the carboxy-terminal domain of human BM-40 (SPARC, osteonectin), an extracellular matrix protein containing an EF-hand pair. The two EF-hands interact canonically but their detailed structures are unusual.

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Crystal structure of a pair of follistatin‐like and EF‐hand calcium ...

emboj.embopress.org

Here we report the crystal structure at 3.1 Å resolution of the FS–EC domain pair of human BM‐40. The two distinct domains interact through a small interface that involves the EF‐hand pair of the EC domain. Residues implicated in cell binding, inhibition of cell spreading and disassembly of focal adhesions ...

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Hand Pair and Ef-Hand Free People Check